Does Excessive Gestational Weight Gain Contribute to Preeclampsia?

Excessive gestational weight gain and obesity contribute to altered expression of maternal insulin-like growth factor binding protein-3

BACKGROUND Excessive gestational weight gain (GWG) increases risk of large for gestational age neonates and subsequent tracking of excess weight throughout the life course for both mother and child. Although the physiological mechanisms underlying these associations are incomplete, the insulin-like growth factor (IGF) axis has garnered attention for its role in fetal growth and development. Our...

Excessive gestational weight gain and postpartum weight retention among obese women.

OBJECTIVE To evaluate the incremental effect of weight gain above that recommended for term pregnancy (15 pounds) on postpartum weight retention at 1 year among obese women. METHODS In a retrospective cohort study, we identified 1,656 singleton gestations resulting in live births among obese women (body mass index at or above 30 kg/m) between January 2000 and December 2005 in Kaiser Permanent...

Does gestational weight gain in normal pre-pregnancy BMI pregnant women reflect fetal weight gain?

OBJECTIVE To identify the correlation between gestational weight gain in pregnant women with normal pre-pregnancy body mass index (BMI) and fetal weight gain. MATERIAL AND METHOD Uncomplicated normal pre-pregnancy BMI Thai singleton pregnant women with less than 16 weeks' gestation participated in this study between June 2008 and September 2009. Serial measurements of maternal and fetal weigh...

Does weight gain lead to weight loss?

Risk Factors for Excessive Gestational Weight Gain in a Healthy, Nulliparous Cohort

OBJECTIVE Excessive gestational weight gain (GWG) is associated with adverse maternal and child outcomes and contributes to obesity in women. Our aim was to identify early pregnancy factors associated with excessive GWG, in a contemporary nulliparous cohort. METHODS Participants in the SCOPE study were classified into GWG categories ("not excessive" versus "excessive") based on pregravid body...